Dear Dr ****
Ms ****: Title
Your paper has been seen again by the Reviewing Editor and Expert Referee, and I am pleased to report that it is considered to be acceptable, after further changes. I enclose a report from the editor and a marked copy of the manuscript whic~h contains many suggested alterations. I should be grateful if you could revise the manuscript as indicated and send me one copy of the further revised manuscript, which will then be accepted. The Journal of * is now asking authors to submit copies of manuscripts on disk, and I wish to draw your attention to the enclosed leaflet.
Yours sincerely encl .

Editor's report Ms ****, revised This Ms is now basically acceptable, but the style is at times deficient. The one remaining scientific problem concerns the interpretation of Fig. 3B. It is suggested (pp. 11 and 19) that the response decrease is due to washout. However at the same time new figures (particularly Fig. 7) dearly show that a similar decline can be observed in nystatin recordings due to desensitization. Ruling out desensitization in the case of Fig. 3B would require a rigorous statistical test based on a quantitative assessment of the response decline. Since such an analysis clearly falls outside the scope of the present work, it is far simpler to just delete the incriminated paragraphs as indicated on the Ms. Other suggestions for stylistic changes have similarly been included in the attached Ms.

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